A unique product development partnership seeks to address the need for new therapeutics for Chagas disease by developing and testing vaccine candidate antigens that would eventually comprise a ...

As a deliverable, the advancement in development of an urgently needed new medical intervention, a therapeutic vaccine for Chagas disease, one of the most important neglected tropical diseases in ...

Main Goal: The overall goal of the project is to advance the first therapeutic Chagas disease vaccine prototype through a First-in-Human Phase 1 clinical trial. SARS-CoV Vaccine Development Main Goal: ...

Trypanosomes are parasites that cause sleeping sickness, Chagas disease, and various animal diseases. Diagnosis and treatment remain complex and no effective vaccine has been developed. A better ...

Screening disease-causing pathogens for potential vaccine targets is a costly and ... used to profile pathogens causing Chagas disease, Leptospirosis and even COVID-19. "Phage display had never ...

Based on genome datasets spanning two decades, researchers concluded that Chagas disease, a deadly tropical disease caused by a parasite, drove a strong pulse of natural selection in the Amazon ...

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, finds its roots in the intricate web of transmission ...

The advantages of a therapeutic Chagas disease vaccine compared with benznidazole alone (the current major competing product in clinical use) could include the following: Three recent ...

Trypanosomes are parasites that cause sleeping sickness, Chagas disease, and various animal diseases. Diagnosis and treatment remain complex and no effective vaccine has been developed.