A nasal vaccine for COVID-19 – based on technology developed at Washington University in St. Louis – is poised to enter a phase 1 clinical trial in the U.S. after an investigational new drug ...

Pathology is the precise study of the causes and consequences of a disease. The two major components of pathology are anatomical studies of structure and function at levels ranging from the whole ...

In addition, human replication-deficient adenovirus type 5 live vector CSF vaccine and chimeric CSFV vaccine can induce complete immune protection. Adenovirus vector vaccines have been the mainstream ...

These data indicate that p53 has a determining role in allowing adenovirus to induce CPE and probably, therefore, in virus replication. Moreover, although the E1b58kDa protein is not required for ...