Endocannabinoids bind to cannabinoid receptors throughout ... of chemicals and receptors. Just as opioids stimulate the brain's reward system to release dopamine, so do the naturally occurring ...

A new type of non-opioid painkiller, aimed at treating short-term pain in adults, has been approved by the US Food and Drug ...

These glial products may thereby enhance neuronal excitability and potentiate drug-induced changes at the neuronal sites of action (e.g. dopamine transporter, opioid receptors, etc.) throughout the ...

LTP GABA in turn may be a mechanism that increases the inhibitory input, and thus reduces the excitability, of VTA dopamine neurons. Opioids are known to target the VTA; previous experiments had ...

The FDA granted approval for Journavx after clinical trials demonstrated its effectiveness in post-surgical pain relief ...

Combining methadone with other long-acting and short-acting opioids for pain management. Ask the Experts about Pharmacotherapy. Medscape Pharmacists. Posted 03/02/2006. Available at: https ...

Their findings, published in Nature Neuroscience, suggest that different aspects of reward-related behavior are supported by two distinct dopamine receptors, namely D3 and D1. "The previous ...