Hosted on MSN4d
Biogen Stock Down on Regulatory Update in the EU for Alzheimer's Drug
Biogen BIIB and Japan-based partner, Eisai, announced an update regarding the regulatory review of an application seeking the ...
pharmaphorum5d
Mixed reactions among HCPs as lecanemab and donanemab secure FDA approval for Alzheimer's treatment
Its approval succeeds both the FDA’s accelerated and traditional approvals of Eisai and Biogen’s lecanemab (also known as Leqembi), a ... providing a novel mechanism to slow the progression ...
Frontiers5d
From attention-deficit hyperactivity disorder to sporadic Alzheimer’s disease—Wnt/mTOR pathways hypothesis
Currently, the only clinically approved disease-modifying drugs for AD are aducanumab (Aduhelm) and lecanemab (Leqembi). All other AD treatment ... possibly mediated by a common mechanism. However, ...
pharmaphorum2d
EMA experts will look again at Leqembi's safety data
It seems Eisai and Biogen have another hurdle to jump over in their bid to get EU approval for their Alzheimer's disease therapy Leqembi. In the latest development, the European Commission has ...
newsroom.unfccc.int3d
Information on UNFCCC negotiations on the mechanisms under the Kyoto Protocol:
As an additional means of meeting these targets, the Kyoto Protocol introduced three market-based mechanisms, thereby creating what is now known as the carbon market. Stimulate sustainable development ...
Neurology Advisor3d
Leqembi Monthly IV Maintenance Dosing Approved for Early Alzheimer Disease
The Food and Drug Administration (FDA) has approved the supplemental Biologics License Application (sBLA) for the monthly intravenous (IV) maintenance regimen of Leqembi ® (lecanemab-irmb ...
Nature4d
Mechanisms of disease articles from across Nature Portfolio
ORF3a, an accessory protein of SARS-CoV-2, mediates the transmembrane transport of water, leading to lysosome swelling. This function could, in principle, result in lysosome inactivation, a ...
Frontiers5d
Complement system part I – molecular mechanisms of activation and regulation
This article will review the mechanisms of activation of alternative, classical, and lectin pathways, the formation of C3 and C5 convertases, the action of anaphylatoxins, and the ...
verywellhealth6d
How Multiple Sclerosis Is Treated
Vumerity (diroximel fumarate) is an oral capsule taken twice a day. The exact mechanism remains unknown, although experts suspect it may work by reducing oxidative stress, which helps protect against ...
The Pharma Letter5d
BRIEF—EC calls for update on regulatory review of lecanemab
Japan’s Eisai and US partner Biogen have announced today update on the ongoing regulatory review of the Marketing Authorization Application for lecanemab (trade name Leqembi) as a treatment for early ...
Managed Healthcare Executive4d
FDA Approves Susvimo for Diabetic Macular Edema
Susvimo is also approved to treat age-related macular degeneration, and the medication, ranibizumab, is delivered though a refillable ocular implant. The FDA has approved Genentech’s Susvimo ...
Medscape1d
Alzheimer's Disease
The reassessment of Leqembi’s safety data follows the agency’s previous recommendation of the drug for use in the EU.