University of Illinois Chicago scientists have redesigned a treatment for the most common pediatric leukemia to eliminate its severe side effects, like blood clots and liver damage. If approved, the ...

Design Therapeutics' GeneTAC platform is revolutionizing genetic disease treatment with small molecules and promising results ...

Thermo Fisher Scientific, Horizon Discovery, OriGene Technologies, QIAGEN, and GeneCopoeia Lead the Competition MicroRNA ...

Multi-Modal Models: A multi-modal discovery approach was implemented that engineered-in potency against the novel target and engineered-out a specific off-target interaction. The NCE library displayed ...

Researchers at the Department of Organic Chemistry and the Center for Molecular Biosciences (CMBI), led by Kathrin Breuker, ...

In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

Scientists recently studied how different factors affect antisense oligonucleotides (ASOs) under hydrophilic interaction ...

Cell penetrating peptides expand pivotal roles in oncology, neurology, and immunotherapy, connecting specialized carriers ...

a method used to identify and classify Bacteria and Archaea in environmental or biological samples by sequencing specific regions of the 16S ribosomal RNA gene, which is present in all prokaryotes and ...

Regarding post-translational modifications, the authors catalogued alternative polyadenylation, which affects transcript length and stability, as well as adenosine to inosine RNA editing. Inosines are ...