The discovery and development of GLP-1 receptor agonists for type 2 diabetes and obesity is a bench-to-bedside success story.1 Multiple GLP-1 receptor agonists are now in clinical use, such as ...
To determine whether increased androgen receptor protein concentration has a causal role in the hormone sensitive-to-hormone refractory transition, we introduced epitope-tagged wild-type AR cDNA ...
Figure 4: Overview of erythropoietin receptor activation and intracellular pathways. Mechanisms that might underlie EPO resistance are defective dimerization or defective activation of the EPO ...
An innovative organoid model mirrors the pancreas' complexity, generating all three key cell types to explore development and ...
and RIG-I-like receptors (RLRs), that can detect molecules from pathogens (pathogen-associated molecular patterns—PAMPs) or molecules released from damaged cells (damage or danger-associated molecular ...
This important study investigates the function of a critical regulator of human early cardiac development. The convincing examination of GATA6 function is thorough and well-executed. The study will be ...
Figure 3. Antibiotic resistance and persister formation in ... Interference with the signal receptor. Searching for enzymes capable of breaking down the AHL signal molecules is a promising strategy to ...
Key Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Sciences, Zhejiang University, China; Hainan Institute of Zhejiang University, Yongyou ...
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