It is unsettling when parents refuse treatment for their child’s serious illness based on their expectation of a miraculous ...

2 Department Community Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow G3 8SJ, UK 3 Fraser of Allander Neurosciences Unit, Royal Hospital for Sick Children, Yorkhill, Glasgow G3 8SJ, ...

Objective Due to lack of information on drug use in children, many drugs are used off-label in paediatrics. Increased knowledge of adverse drug reactions (ADRs) would enable a better risk–benefit ...

AIM To clarify the contribution of clinical and environmental factors and infection to the aetiology of vulvovaginitis in premenarchal girls, and to determine clinical indicators of an infectious ...

Objective In this systematic review and meta-analysis, we assessed and summarised the certainty of the evidence about the effects of gender affirming hormone therapy (GAHT) in individuals with gender ...

London Centre for Paediatric Endocrinology, Great Ormond Street and The Middlesex Hospitals, London W1H 8AA, UK Professor C G D Brook, Cobbold Laboratories, The Middlesex Hospital, Mortimer Street, ...

BACKGROUND In adults, erythema multiforme (EM) is thought to be mainly related to herpes infection and Stevens–Johnson syndrome (SJS) to drug reactions. AIMS To investigate this hypothesis in children ...

Bacterial tracheitis is the most common paediatric airway emergency requiring admission to the regional paediatric intensive care unit in northern Ireland. We reviewed 89 admissions to our unit with ...

Before or during birth, a small number of infants experience reduced oxygen or blood supply. After birth, some of these infants will show abnormal neurological behaviour, diagnosed as hypoxic-ischemic ...

Aims Extremely premature infants are at higher risk for intracranial ischaemic and haemorrhagic injuries, which often occur in the first 72 hours after birth. 1 Intraventricular haemorrhages (IVHs) ...

Background The safety of long-acting β 2 agonist (LABA) therapy in asthma remains controversial but no large scale analyses have been published of LABA safety in children. Methods The frequency of ...

Introduction and Objective Hip instability in children with cerebral palsy (CP) is a serious progressive problem. Materials and Methods 141 surgical procedures were performed on children 3 – 16 years ...