All lanes of the southbound 405 Freeway in Encino have reopened after an hours-long closure for a deadly crash.

A deadly wrong-way crash on the southbound 405 Freeway in Sherman Oaks shut down traffic on all lanes early Tuesday.

A deadly crash involving a wrong-way driver closed all southbound lanes of the 405 Freeway heading into Los Angeles’ ...

At least one person was killed in a reported wrong-way crash on the 405 Freeway in Encino that temporarily shut down of all southbound lanes Tuesday morning.

An SUV was reported driving 60 to 70 mph northbound in the southbound carpool lanes of the 405 freeway near Getty Center Drive just after 4 a.m. Tuesday, according to California Highway Patrol logs.

At least one person is dead following a wrong-way crash on the southbound lanes of the 405 Freeway in Sherman Oaks.

A motorist driving north on the southbound side of the San Diego (405) Freeway in Sherman Oaks slammed head-on into another vehicle Tuesday, leaving the wrong-way driver dead and two other people ...

California Highway Patrol officers responded at 4:06 a.m. to the southbound 405 near the Valley Vista Boulevard exit.