Our work has generated investment ideas in health care, consumer electronics, finance technologies, transportation, AI-based Oppenheimer raised the firm’s price target on Ligand (LGND ...

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, engages in the development and licensing of biopharmaceutical assets worldwide. Its commercial programs include Kyprolis and ...

Attribution (BY): Credit must be given to the creator. Most traditional optical biosensors operate through molecular recognition, where ligand binding causes conformational changes that lead to ...

The four top-scoring compounds with the lowest binding energies were selected and their activities were compared to those of the co-crystallized ligand. A 100 ns MDS was used to assess the binding ...

CCR2, a classic G protein-coupled receptor, activates a variety of downstream signaling pathways upon binding to its ligand CCL2, such as PI3K/Akt, JAK/STAT, and P38/MAPK. Activation of these pathways ...

Faculty of Medical Technology, Prince of Songkla University, Songkhla 90110, Thailand Division of Biological Science, Faculty of Science, Prince of Songkla University, Songkhla 90110, Thailand ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. A multiplex drug screening platform with ...

P2Rank: Protein-ligand binding site prediction from protein structure based on machine learning.

This work presents important findings regarding the interaction of the monkeypox virus (MPXV) attachment H3 protein with the cellular receptor heparan sulfate and the use of this information to ...