Forget the traditional tubular shape—researchers are investigating a pearl-on-a-string formation for axons, unlocking new ...

The axon initial segment (AIS) is where nerve signals begin, and its adaptability is key to brain function. Scientists have found that the AIS changes in response to activity levels, helping neurons ...

The Hodgkin-Huxley (H-H) theory of the action potential, formulated 50 years ago, remains one of the great success stories in biology, and ranks among the most significant conceptual breakthroughs ...

Treating the neurons and me — my mental states — in a synergistic way proved to speed up and enhance healing. It does for ...

Drugs targeting amyloid plaques have failed to show efficacy in clinical trials. A new approach is needed to tackle AD ...

If the drug is approved by the US Food and Drug Administration for the treatment of acute pain in January as expected, the ...

Sphere of Influence. In iAssembloids, microglia (red) form projections (white arrows), while astrocytes (green) assume star shapes typically found in the brain. [Courtesy of Kampmann et al., 2025.] ...

Neurons generate and propagate electrical pulses called action potentials which annihilate on arrival at the axon terminal. We measure the extracellular electric field generated by propagating and ...

The authors explain that an action potential that reach an axon terminal emits a small electrical field as it "annihilates". This happens even though there is no gap junction, at chemical synapses.

IT has been suggested 1 that the vesicle-like structures inside the axon near the neuromuscular ... to produce the spontaneous miniature endplate potentials.

The percentage of axons activated was computed for each simulation scenario. A time varying field potential was created by convoluting the obtained potentials by a normalized time varying electric ...