Synthetic biologists from Yale were able to re-write the genetic code of an organism—a novel genomically recoded organism (GRO) with one stop codon—using a cellular platform that they developed ...

Chromatin, the mix of DNA and protein that houses each cell's genome, is more resilient to aging than previously thought, suggests a study published in the Journal of the American Chemical Society by ...

Low-density lipoproteins (LDL) -- commonly known as bad cholesterol -- have long been on scientists' radar as a major contributor to heart disease. But these microscopic troublemakers have hidden ...

The way the body ages could be more resilient than previously thought, a new study suggests.

Several stress mediators (reactive oxygen species, ceramide, elevation of cytosolic Ca 2+), isoforms of p19ARF (or its human homologue, p14ARF), p53, BH3-only proteins and death-associated protein ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

International researchers have engineered protein-based nanomachines that detect lanthanides, offering new methods for rare ...

approach has been widely applied as an efficient and reliable free energy simulation method to model molecular recognition, such as for protein-ligand binding interactions. In this review, we focus on ...

Again, the attenuation relies in large part on the capacity of a versatile recognition molecule FH to discriminate between self and non-self and to stop the amplification loop. C3b and C3(H 2 O) may ...

We read with great interest the study by Wunsch et al 1 published in this issue of Polish Archives of Internal Medicine, which validated the prognostic ability of 2 previously ide ...