KNOXVILLE, Tenn. — A multi-vehicle crash blocked some eastbound lanes of Interstate 40 near downtown Knoxville Thursday ...

KNOXVILLE, Tenn. — Interstate Health opened a new clinic near a Pilot Travel Center on Interstate 40 on Tuesday. The clinic provides urgent care, primary care and occupational health services ...

The only two direct interstate routes between Tennessee and North Carolina are going to be cut off for a long time, transportation officials said Tuesday. Interstate 40 in North Carolina's Pigeon ...

A Tennessee Highway Patrol officer shot a driver they were chasing after he crashed at the Interstate 40 exit to Watt Road. Special Agent Jason Pack, a spokesman for the Tennessee Department of ...

A 38-year-old Knoxville man died in a single-car crash on Interstate 40 at the Hall of Fame Drive exit on the night of Dec. 13. David Boatwright crashed into a barrier and rolled off the road at about ...

It's official: Knoxville has been placed under a winter storm warning ... snow accumulations" with a mixture of sleet and ...

Knoxville has lots of busy streets leading to retail centers and highways crisscrossing the landscape. There are bound to be ...