Forget the traditional tubular shape—researchers are investigating a pearl-on-a-string formation for axons, unlocking new ...

The axon initial segment (AIS) is a crucial part of neurons, acting as the site where action potentials are generated and playing a significant role in maintaining the polarity of the neuron.

Understanding how the convergence of multiple mechanisms results in neuronal loss may offer opportunities for neuroprotective interventions. Mechanisms of the Pro-Regenerative Response to Axon Injury ...

The axon initial segment (AIS) is where nerve signals begin, and its adaptability is key to brain function. Scientists have found that the AIS changes in response to activity levels, helping neurons ...

Treating the neurons and me — my mental states — in a synergistic way proved to speed up and enhance healing. It does for ...

New research on nematodes reveals how glial cells maintain and monitor neuronal dendrites. Neurons may get all the glory, but they would be nothing without glial cells. While brain cells do the heavy ...

A study in the journal Pharmaceuticals has uncovered how specific genetic mutations in α2δ-1 and α2δ-3 proteins linked to ...

Cell adhesion molecules (CAMS), i.e., laminin-1 or N-cadhedrin Adhesion and attractant Allow cells to grow along the surfaces of other cells (such as using pioneering axons for subsequent axons ...

Sphere of Influence. In iAssembloids, microglia (red) form projections (white arrows), while astrocytes (green) assume star shapes typically found in the brain. [Courtesy of Kampmann et al., 2025.] ...

Drugs targeting amyloid plaques have failed to show efficacy in clinical trials. A new approach is needed to tackle AD ...