The discovery and development of GLP-1 receptor agonists for type 2 diabetes and obesity is a bench-to-bedside success story.1 Multiple GLP-1 receptor agonists are now in clinical use, such as ...
(5) For Figure 5B, it would be interesting if the authors could ... but the authors show that a chimeric FZD5CRD-FZD4 receptor can confer Wnt-dependent endocytosis to an otherwise endocytosis ...
1Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China. 2Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China. 3Key ...
To investigate the cell-cell interactions between different cell types in the normal scar samples and keloid samples, cellular spatial organization mapper (CSOmap) software (v1.0) was used to identify ...
Figure S5A,B shows the fluctuations of helix3 COM compared ... for peripheral proteins and the EGFRtm dimer and the Human A2A Adenosine of G protein-coupled receptors (GPCRs) as representatives for ...
Figure 1. Eph signaling, and pathways involved in upper digestive tract cancers. The interaction between Eph receptors and ephrin ligands constitutes a crucial cellular communication system ...
School of Pharmacy, The University of Queensland, Brisbane 4102, Australia Inflammatory Bowel Diseases Group, Mater Research Institute─UQ at Translational Research Institute, The University of ...
This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license. This work is licensed under a Creative Commons Attribution 4.0 International ...
Though the Norrin protein is structurally unrelated to the Wnt ligands, it can activate the Wnt/βcatenin pathway by binding to the canonical Wnt receptors Fzd4 and ... the Norrin and Tspan12 mutants ...
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