gut.bmj1d
Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis
Objective Hepatic stellate cells (HSC) transdifferentiation into myofibroblasts is central to fibrogenesis. Epigenetic mechanisms, including histone and DNA methylation, play a key role in this ...
gut.bmj1d
Differential expression of laminin receptors in human hepatocellular carcinoma
Division of Hepatology and Metabolism, Department of Internal Medicine, Saga Medical School, Saga, Japan Dr I Ozaki, Division of Hepatology and Metabolism, Department of Internal Medicine, Saga ...
gut.bmj2d
Irritable bowel syndrome: treatment based on pathophysiology and biomarkers
Objective To appraise the evidence that pathophysiological mechanisms and individualised treatment directed at those mechanisms provide an alternative approach to the treatment of patients with ...
gut.bmj3d
Microbiota-induced S100A11-RAGE axis underlies immune evasion in right-sided colon adenomas and is a therapeutic target to boost anti-PD1 efficacy
2 Key Laboratory of Human Microbiome and Chronic Diseases (Sun Yat-sen University), Ministry of Education, Guangzhou, China Background Tumourigenesis in right-sided and left-sided colons demonstrated ...
gut.bmj9d
Cholelithiasis: A clinical and dietary survey
Cholelithiasis among male and female patients at the Royal Melbourne Hospital was studied, and the incidence of the disease in relation to various clinical and dietary factors is discussed. The ...
gut.bmj12d
Induction of macrophage efferocytosis in pancreatic cancer via PI3Kγ inhibition and radiotherapy promotes tumour control
Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...
gut.bmj13d
Detection of large flat colorectal lesions by artificial intelligence: a persistent weakness and blind spot
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...
gut.bmj15d
Intestinal ganglioneuromatosis and multiple endocrine neoplasia type 2B: implications for treatment
Dr V V Smith, Histopathology, Camelia Botnar Laboratories, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK. Three infants, who presented with intestinal obstruction due to ...
gut.bmj15d
Pain in chronic pancreatitis: the role of neuropathic pain mechanisms
1 Mech-Sense, Department of Gastroenterology, Aalborg University Hospital, Aalborg, Denmark 2 Center for Sensory-Motor Interactions, Department of Health Science and Technology, Aalborg University, ...
gut.bmj16d
Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents
Objective Patients with renal failure suffer from symptoms caused by uraemic toxins, possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is to characterise ...
gut.bmj18d
Aspirin is associated with lower risk of pancreatic cancer and cancer-related mortality in patients with diabetes mellitus
Background Patients with type 2 diabetes mellitus (T2DM) have higher pancreatic cancer (PC) risk. While aspirin has chemopreventive effects on digestive cancers, its effect on PC among patients with ...
gut.bmj18d
Construction of exosome non-coding RNA feature for non-invasive, early detection of gastric cancer patients by machine learning: a multi-cohort study
Background and objective Gastric cancer (GC) remains a prevalent and preventable disease, yet accurate early diagnostic methods are lacking. Exosome non-coding RNAs (ncRNAs), a type of liquid biopsy, ...