Dr Masahiro Sonoo, Department of Neurology, Teikyo University School of Medicine, Kaga 2–11–1, Itabashi-ku, Tokyo 173, Japan. Telephone 0081 3 3964 1211 ext 1911; fax 0081 3 3964 6397; email sonoom{at ...
Clinically isolated syndrome (CIS) patients present with a single attack of inflammatory demyelination of the central nervous system. Recent advances in multiple sclerosis (MS) diagnostic criteria ...
Background: Mild cognitive impairment (MCI) has been considered a transitional state between normal aging and dementia, characterised by memory impairment but normal general cognitive functioning.
Background Global hippocampal atrophy is a hallmark of Alzheimer’s dementia and has been similarly reported in Parkinson’s disease dementia (PDD). However, there is limited literature on the ...
Objective To evaluate the efficacy and safety of intramuscular ultra-high-dose methylcobalamin in patients with amyotrophic lateral sclerosis (ALS). Methods 373 patients with ALS (El Escorial definite ...
1 Department of Psychiatry and the Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA 2 Department of Psychiatry, ...
Loss of nigrostriatal dopaminergic projection neurons is a key pathology in Parkinson’s disease, leading to abnormal function of basal ganglia motor circuits and the accompanying characteristic motor ...
Ranking of head injuries by severity is an essential part of clinical management, of prognosis, of treatment trials, and of legal assessment for compensation. Various methods of assessing severity are ...
Background Early fast-acting treatment (EFT) is the aggressive use of fast-acting therapies such as plasmapheresis, intravenous immunoglobulin and/or intravenous high-dose methylprednisolone (IVMP) ...
1 Departments of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, USA 2 Departments of Rehabilitation Medicine and Pediatrics, University of Washington, Seattle, ...
Department of Neurology, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland Correspondence to Dr Tuula Pirttilä, Department of Neurology, Bldg 5, Kuopio University Hospital POB ...
Dr G Midroni, Neurophysiology laboratory, St. Michael’s Hospital, 30 Bond Street, Toronto, Ontario, Canada M5B 1W8. Telephone 00416 864 5193; fax 00416 864 6095. A 22 year old woman with recently ...