Oct 1, 2021 · Conversely, high cholesterol levels, high blood pressure, and diabetes are all risk factors for heart disease, as well as for a condition called vascular dementia, in which impaired blood flow to the brain leads to cognitive changes.

Cholesterol in the brain is important for the health of brain cells, and this may be affected in dementia. The gene that most affects the risk of late-onset Alzheimer's disease, ApoE4, plays a role in the processing and use of cholesterol.

Early findings indicated that hypercholesterolemia - expecially high midlife total cholesterol - can be an important risk factor of neurodegenerative diseases and dementia. However, causing role of high cholesterol levels in AD or MCI has not been confirmed and findings concerning circulating cholesterol and dementia are contradictory.

Nov 11, 2024 · Those whose cholesterol levels changed the most over the course of three annual tests had up to a 60% increased risk of being diagnosed with dementia within the next six years, and a 23%...

Jul 23, 2021 · Overall, we found a modest positive association between LDL cholesterol and dementia, with an adjusted rate ratio (RR) of 1·05 (95% CI 1·03–1·06) per SD increase in LDL cholesterol (1·01 mmol/L or 39 mg/dL increase).

2 days ago · During the study, 509 people developed dementia. A total of 147 of the 2,408 people in the group with the largest amount of change in total cholesterol developed dementia, a rate of 11.3 per 1,000 ...

Jul 15, 2021 · High blood cholesterol can raise the risk of certain types of dementia, such as Alzheimer’s disease and vascular dementia. However, cholesterol does not enter the brain, and researchers are unsure how these conditions are linked.

Nov 12, 2024 · Older adults with cholesterol levels that go up and down from year to year may face greater risks for cognitive decline and dementia than their peers with more stable cholesterol levels, preliminary new research suggests.

1 day ago · THURSDAY, Jan. 30, 2025 (HealthDay News) -- Seniors whose cholesterol levels spike and plummet year-to-year could be at increased risk of dementia and failing brain health, a new study suggests.. Those whose cholesterol fluctuated the most had a 60% increased risk of dementia, researchers report in findings published Jan. 29 in the journal Neurology. ...

The new study, published Wednesday in Neurology, found that having either high or low levels of high-density lipoprotein, or HDL, cholesterol, may increase the risk of dementia in older adults.